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汤雪明(基础医学院)
 
汤雪明教授,男,1939年3月出生。

简历:
    1962           毕业于上海第二医科大学                   
    1962-1979  上海第二医科大学助教 、讲师             
    1980-1982   McGill 大学访问学者
    1980-1984  上海第二医科大学副教授                  
    1987-1988   McGill 大学客座教授
    1985-          上海第二医科大学教授

荣誉奖励:
1983年  上海市劳动模范
1986年  国家人事部:有突出贡献的中青年专家
1991年  国务院特殊津贴
1996年  中国电子显微学学会銭临照奖
2001年  全国优秀教师                                                                                                
研究方向:
1、 细胞器的结构与功能
2、 细胞化学技术的建立和应用
3、 医学细胞生物学:细胞增殖、分化与凋亡                                                             
研究成果:
曾获国家和上海市科技成果奖12项,其中
国家科技进步三等奖1项
上海市科技进步一等奖1项
上海市科技进步二等奖3项
上海市科技进步三等奖1项
国家教委科技进步二等奖3项
国家教委科技进步三等奖1项
卫生部科技成果奖2项

主编书籍:
《医学细胞与分子生物学》,上海医科大学出版社,1995年
《医学细胞生物学》,科学出版社,2003年
《医学细胞与分子生物学》,第二版, 科学出版社,2004年


主要论文:
1. Tang XM, Lalli MF, and Clermont Y ( 1982 ). A Cytochemical Study of the Golgi Apparatus of the Spermatid During Spermiogenesis in the Rat. The American Journal of Anatomy, 163:283-294
2. Tang XM and Chai BF ( 1982 ). Light Microscopic and Electron Microscopic Observation on Experimental Fracture Healing. Chinese Medical Journal, 95:721-730                                          
3. Lalli MF, Tang XM, and Clermont Y ( 1984 ). Glycoprotein Synthesis in Sertolli Cells During the Cycle of the Seminiferous Epithelium of Adult Rats: A Radioautographic Study. Biology of Reproduction, 30:493-505                 
4. Clermont Y and Tang XM ( 1985 ). Glycoprotein Synthesis in the Golgi Apparatus of Spermatids During Spermiogenesis of the Rat. The Anatomical Record, 213:33-43                                         
5. Tang XM and Chai BP ( 1986 ). Effect of CO2 Laser Irradiation on Experimental Fracture Healing: A Transmission Electron Microscopic Study. Lasers in Surgery and Medicine, 6:346-352
6. Tang XM and Chai BF ( 1986 ). Ultrastructural Investigation of Osteogenic Cells.                      
    Chinese Medical Journal, 99:950-956                          
7. Tang XM, Chu SY, and Zhang HX ( 1987 ). Ultrastructural and Cytochemical Characteristics of Megakaryoblastic Leukemic Cells. Journal of Electron Microscopy Technique, 7:119-125                                                 
8. Tang XM, Clermont Y, and Hermo L ( 1988 ). Origin and Fate of Autophagosomes in Leydig Cells of Normal Adult Rats . Journal of Andrology, 9:284-293
9. Tang XM and Clermont Y ( 1989 ). Granule Formation and Polarity of the Golgi Apparatus in Neutrophil Granulocytes of the Rat.The Anatomical Record, 223:128-138
10. Tang XM and Chai BF ( 1989 ).Effect of Intra-articular Fracture on Articular Chondrocytes: A Transmission Electron Microscopic Study. Chinese Medical Journal, 102:207-213                                                                   
11. Throne-Tjomsland G, Clermont Y, and Tang XM ( 1991 ). Glucose-6-phosphatase Activity of Endoplasmic Reticulum and Golgi Apparatus in Spermatocytes and Spermatids of the Rat: An Electron Microscopic Cytochemical Study. Biol Cell, 71:33-41                                   
12. Yi J and Tang XM ( 1995 ). Functional Implication of Autophagy in Steroid-Secreting Cells of the Rat . The Anatomical Record, 242:137-146
13. Chevalier J, Yi J, and Tang XM ( 1997 ). Biotin and Digoxigenin as Labels for Light and Electron Microscopy in Situ Hybridization Probes: Where Do We Stand?  The Journal of Histochemistry and Cytochemistry, 45:481-491
14. Yi J and Tang XM ( 1999 ). The Convergent Point of the Endocytic and Autophagic Pathways in Leydig Cells. Cell Research, 9:243-253
15. Yi J, Yu DR, Chen YY, Xiong WH, Li XX, Shen JK and Tang XM ( 2000 ). P16 Overexpression in Pituitary Adenomas Studied by Immunohistochemistry and in situ Hybridization. Chinese Medical Journal, 113:162-166                      
16. Tai SW and Tang XM ( 2001 ). Manipulating Biological Samples for Environmental Scanning Electron Microscopy Observation. Scanning, 23:267-272
17. Yi J,Gao F,Shi G,Li H,Wang Z Shi X and Tang XM ( 2002 ). The Inherent Cellular Level of Reactive Oxygen Species:One of the Mechanisms Determining Apoptotic Susceptibility of Leukemic Cells to Arsenic Trioxide. Apoptosis,7:209-215
18. Gao F, Yi J, Shi GY, Li H, Shi XG and Tang XM ( 2002 ). The Sensitivity of  tract tumor Cells to As2O3 is associated with the inherent Cellular Level of ROS. World Journal of Gastroenterology, 8:36-39
19. Yi J, Gao F, Shi GY, Li H, Shi XG and Tang XM ( 2002 ). Apoptosis Susceptibility of Tumor Cells to Arsenic Trioxide and the Inherent Cellular of ROS. Chinese Medical Journal, 115:603-606
20. Huang HX and Tang XM ( 2003 ). Phenotypic Determination and Characterization of Nestin-Positive Precursors Derived from Human Fetal Pancreas. Laboratory Investigation, 83:539-547                                        
21. Fei Gao, Jing Yi, Jing Qi Yuan, Gui Ying Shi, Xue Ming Tang ( 2004 ). The cell cycle related apoptotic susceptibility to arsenic trioxide is associated with the level of ROS. Cell Research, 14:81-85
22. Ya-Wu Jing, Jing Yi, Yu-Ying Chen, Qing-Shen Hu, Gui-Ying Shi, Hue Li, and Xue-Ming Tang ( 2004 ). Dicoumarol Alters Cellular Redox State and Inhibits Nuclear Factor Kappa B to Enhance Arsenic Trioxide-Induced Apoptosis. Acta Biochimica et Biophysica Sinica, 36: 235-242

联系方式:
地址:上海市重庆南路280号
电话:64453260
E-mail: xmtang@shsmu.edu.cn

 
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