徐凌云,女,博士,上海第二医科大学免疫学教研室研究员、课题组长。山东医科大学临床医学学士,瑞典卡罗琳斯卡医学院博士,美国宾西法尼亚大学医学院博士后。
研究方向:
利用实验动物模型,研究自身免疫病的病理生理机制,寻找有效的免疫调节和免疫治疗方法。包括: 新发现的免疫活性的因子对自身免疫反应的调节作用;自身反应性T 细胞在中枢神经系统脱髓鞘和炎症反应中的作用; 神经-内分泌-免疫网络的调节作用;等等。
主要成果:在国际学术期刊上发表论文二十篇。
1. L-Y Xu, BA Hilliard, R J. Carmody, G Tsabary, H Shin, DW Christianson, and YH Chen. Roles of Arginase in Experimental Autoimmune Encephalomyelitis. Immunology. 2003;110:141-8.
2. L-Y Xu, Yang JS, Xiao BG.TGF-beta1-conditioned glial cell-derived dendritic cells inhibit expansion of MBP-reactive T cells in vitro. Neuroreport. 2002; 13:35-9.
3. L-Y Xu, J-S Yang, H Link, and B-G Xiao. SIN-1, a nitric oxide donor, ameliorates EAE on the induction phase in Lewis rats: the importance of time window. J. Immunol. 2001; 166: 5810-5816.
4. L-Y Xu, J-S Yang, Y-M Huang , M Levi, H Link, and B-G Xiao. Combined nasal administration of encephalitogenic MBP peptide 68-86 and IL-10 suppressed ongoing EAE in Lewis rats. Clin. Immunol. 2000; 96: 205-211.
5. L-Y Xu, Y-M Huang, J-S Yang, P H. van der Meide, H Link, and B-G Xiao. Suppression of ongoing EAE in Lewis rats: synergistic effects of MBP peptide 68-86 and IL-4. Clin. Exp. Immunol. 2000; 120:526-531.
6. L-Y Xu, M Ishikawa, Y-M Huang, M Levi, P H. van der Meide, B Wahren, H Link, and B-G Xiao. The complexity of cytokine treatment in ongoing EAE induced with MBP peptide 68-86 in Lewis rats. Clin. Immunol. 2000; 95: 70-78.
7. L-Y Xu, J-S Yang, Y-M Huang, PH. van der Meide, M Levi, B Wahren, H Link, and B-G Xiao. Limitation of nitric oxide production: spleen and lymph node exhibit distinct difference at nitric oxide induction. Immunol. Lett. 2000; 71:177-184.
8. L-Y Xu, Y-M Huang, J-S Yang, PH van der Meide, M Levi, B Wahren , H Link, and B-G Xiao. Dendritic cell-derived Nitric oxide is involved in IL-4-induced suppression of experimental allergic encephalomyelitis in Lewis rats. Clin Exp Immunol. 1999; 118: 115-121.
招生要求:
1. Interested in immunology and scientific research;
2. Honest, hard-working, and team-work spirit;
3. Basic immunology knowledge, and English-literature reading skills